23 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Sensitive Antibodies ... Donath-Landsteiner Antibodies ... Viral Infection Clinical ... of anemia include ... younger pts) Differential
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... or Anti-NucIear Antibody ... context of other symptoms ... likely it will be clinically ... rheumatology #diagnosis #differential
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Pathogenesis and clinical ... history of the disease ... decline in maternal antibody ... immunity Signs/Symptoms ... Agammaglobulinemia #XLinked #pathophysiology
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
enzymes ↑ • Mild anemia ... Detects both HIV antibody ... Phase: • The short ... HIV-1 or HIV-2 antibodies ... ART to slow HIV disease
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... chemotherapy for low-risk disease ... marrow failure with anemia ... 3) Monoclonal antibodies ... hemeonc #diagnosis #management
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases Clinical ... decreased reflexes Pathophysiology ... Residency @CMC_IM #Potts ... #Disease #Tuberculosis
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Auto-antibodies ... : ANCA antibody, ... Anti-GBM antibody ... or serologies + symptoms ... #diagnosis #management
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... Receptor (sTfR) to differentiate ... diet/deficiency symptoms ... fatigue despite disease ... Algorithm #diagnosis #management
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
intrinsic factor, IF) Clinical ... to IBD, celiac disease ... to manifest its symptoms ... , alcohol use, symptoms ... Deficiency #diagnosis #management
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... Leukocytosis, anemia ... Lung Abscess Differential ... Abscess #pulmonary #differential