9 results
Acetaminophen toxicity
Emergency Department Workup and Management - Rumack Matthew Nomogram

#Diagnosis #Management #Toxicology #APAP #Acetaminophen #Rumack #Nomogram
Acetaminophen toxicity ... Rumack Matthew Nomogram ... Diagnosis #Management #Toxicology ... #Rumack #Nomogram ... #Stages #Toxicity
Rumack-Matthew Nomogram for Acetaminophen Toxicity #Diagnosis #Management #Toxicology #RumackMatthew #Nomogram #Acetaminophen #Toxicity #APAP #ALiEM
Rumack-Matthew Nomogram ... for Acetaminophen ... #Management #Toxicology ... #Acetaminophen ... #Toxicity #APAP
N-Acetylcysteine (NAC) restores hepatic glutathione!
Found to have 21-28% reduction in mortality for acetaminophen-induced hepatic failure
The earlier
concentration of acetaminophen ... falls above the normogram ... ) #Diagnosis #Toxicology ... #Nomogram #Acetaminophen ... #Toxicity #APAP
Utilization of Antibiotics as Antidotes

Valproic Acid Toxicity:
Carbapenems 

Amatoxin Mushrooms: 
Polymyxin B, Penicillin, Cyclosporine

Infographic by Mike O'Brien
@MikeEMPharmD

#Antibiotics
Antibiotics as Antidotes ... Valproic Acid Toxicity ... #Antibiotics #Antidotes ... #Toxicology #Pharmacology
Alternative or ContingencyCountermeasures for Acetylcholinesterase Inhibiting Agents
A nerve agent event may deplete local stocks of @US_FDA-approved
US_FDA-approved antidotes ... approved as nerve antidotes ... #Management #Toxicology ... Acetylcholinesterase #Inhibitors #AchEI ... #Antidotes #Countermeasures
Acetaminophen metabolism and factors affecting toxicity. 
GSH = glutathione 

#Acetaminophen #APAP #metabolism #toxicity #Toxicology #Pathophysiology #Overdose
Acetaminophen metabolism ... factors affecting toxicity ... glutathione #Acetaminophen ... APAP #metabolism #toxicity ... #Toxicology #Pathophysiology
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
#Pathophys #Toxicology ... NAcetylCysteine #Acetaminophen ... #Toxicity #emDocs
Fomepizole for Acetaminophen Toxicity

 • In cases where fomepizole and NAC were administered together, evidence has
Fomepizole for Acetaminophen ... Toxicity • ... hour equivalent acetaminophen ... #Fomepizole #Acetaminophen ... #Toxicology #pharmacology
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... evidence of marrow toxicity ... Methotrexate #Leucovorin #Antidote ... #Toxicology #Toxicity