17 results
Alternative or ContingencyCountermeasures for Acetylcholinesterase Inhibiting Agents
A nerve agent event may deplete local stocks of @US_FDA-approved
US_FDA-approved antidotes ... approved as nerve antidotes ... #Management #Toxicology ... Acetylcholinesterase #Inhibitors ... #AchEI #Antidotes
Electrocardiographic Features of Digoxin Toxicity
 • Virtually any arrhythmia is possible. None specific for digoxin toxicity
Toxicity • Virtually ... None specific for digoxin ... toxicity • Classic ... #digitalis #Toxicity ... Electrocardiogram #ekg #ecg #toxicology
Utilization of Antibiotics as Antidotes

Valproic Acid Toxicity:
Carbapenems 

Amatoxin Mushrooms: 
Polymyxin B, Penicillin, Cyclosporine

Infographic by Mike O'Brien
@MikeEMPharmD

#Antibiotics
Antibiotics as Antidotes ... Valproic Acid Toxicity ... #Antibiotics #Antidotes ... #Toxicology #Pharmacology
Almost any type of cardiac arrhythmia is seen in digitalis toxic­ity. However, type II second-degree atrioventricular
seen in digitalis toxic­ity ... characteristic of digitalis toxicity ... changes in digitalis toxicity ... Cardiology #EKG #ECG #Digoxin ... #Toxicity #Toxicology
Hyperkalemia - Differential Diagnosis - Impaired Excretion vs Redistribution

Impaired Urinary Excretion 
 - Renal failure
 -
- Calcineurin inhibitors ... Succinylcholine - Digoxin ... toxicity Other
Amiodarone Toxicity and Monitoring

Tremor Ataxia 
Ocular neuritis 
Corneal Microdeposits 
Bradycardia 
Pulmonary fibrosis 
Hepatotoxicity 
Blue-gray skin
Amiodarone Toxicity ... Substrate CYP3A4 - Inhibitor ... - Key DDI: digoxin ... #Amiodarone #Toxicity
SGLT2 Inhibitors and Euglycemic DKA

Risk factors for euglycemic DKA in those on an SGLT2i include:
 •
SGLT2 Inhibitors ... closed • SGLT2 inhibitor ... Euglycemic #DKA #EDKA #Toxicity ... #Toxicology
Digoxin Toxicity Presentation - Signs and Symptoms
 • Visual disturbances (halos, color disturbances)
 • Weakness
 •
Digoxin Toxicity ... EBmedicine #Digoxin ... #Toxicity #toxicology
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Angiotensin-Converting Enzyme Inhibitors ... and tachycardia Digoxin ... toxicity • Danshen ... increasing risk for toxicity ... Monoamine Oxidase Inhibitors
The chemical formula of Digoxin is C41 H64 O14.
Digoxin (Cardiac glycoside) reversibly inhibits the sodium-potassium-ATPase, causing
glycoside) reversibly inhibits ... However, toxicity ... toxicity and are ... toxicity. ... cardiac glycoside toxicity