1418 results
SGEM#210: (Don’t) Let it Bleed – TXA for Epistaxis in Patients on Anti-Platelet Drugs. Zahed et
Let it Bleed – TXA ... Nasal Packing for Treatment ... KirstyChallen #EBM #TXA ... TranexamicAcid #Epistaxis #AntiplateletDrugs
Tranexamic Acid: Mechanism of Action
 - TXA is an anti-fibrinolytic
 - TXA is a synthetic analog
Mechanism of Action - TXA ... anti-fibrinolytic - TXA ... acid lysine - TXA ... to plasmin - TXA ... pathophysiology #hematology #TXA
Thromboelastogram Interpretation
Reaction Time (R Value):
 - Time till initiation of fibrin clot
 - Treatment: FFP, protamine
K
fibrin clot - Treatment ... interaction - Treatment ... strength of clot - Treatment ... after MA/MCF - Treatment ... : TXA, Amicar
Hypertensive Emergency and Hypertensive Crisis - Blood Pressure Targets
 • Hypertensive Emergency
 • Ischemic Stroke (w/
Ischemic Stroke (w/ tPA ... , w/o tPA) • Hemorrhagic ... Goals #management #treatment
Ischemic Stroke - Blood Pressure Management
 • No tPA  < 220 / 120 (permissive hypertension)
Management • No tPA ... hypertension) • tPA ... hypertension #Management #treatment
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Treatment of Thrombotic ... TTP from other TMA ... (vs. secondary TMA ... HUS) Treatment ... Purpura #management #treatment
Woman – The TXA Trial for Post-Partum Hemorrhage.  Lancet. 2017 May 27
https://www.ncbi.nlm.nih.gov/pubmed/28456509

#EBM #OBGyn #WOMANTrial #TXA
Woman – The TXA ... OBGyn #WOMANTrial #TXA
Xa Inhibitors - Apixaban and Rivaroxaban 
Oral Xa inhibitors are recommended by CHEST as first-line for
Xa Inhibitors - ... Rivaroxaban Oral Xa ... patients with VTE treatment ... rivaroxaban for VTE tx
Multiple Uses for Tranexamic Acid (TXA) - Evidence Based Indications and Dosing

Trauma < 3 hrs •
Tranexamic Acid (TXA ... Hemoptysis YES #TXA
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy (TMA ... Complement-mediated TMA ... - Drug-induced TMA ... Metabolism-mediated TMA ... Microangiopathy #TMA