18 results
Pathophysiology Euglycemic DKA - Mechanism of SGLT-2 Inhibitors #Pathophys #Endocrine #Euglycemic #DKA #SGLT2 #Mechanism
Pathophysiology ... Euglycemic DKA - ... Mechanism of SGLT ... Endocrine #Euglycemic #DKA ... #SGLT2 #Mechanism
Stepwise Approach to Prescription of SGLT2 inhibitors 

Anticipatory Guidance 
• Consider diuretic dose reduction 
Patient Counseling
Prescription of SGLT2 ... • Symptoms Of DKA ... endocrinologists #SGLT2 ... Monitoring #Management #Endocrinology
Pathophysiology and Effects of Insulin Deficiency

#Insulin #Deficiency #DKA #Ketoacidosis #Diabetes #Pathophysiology #Endocrinology
Pathophysiology ... Insulin #Deficiency #DKA ... Ketoacidosis #Diabetes #Pathophysiology ... #Endocrinology
Pathophysiology of Euglycemic DKA in SGLT2 Inhibitors
 • Kidney: Glycosuria, Natriuresis, ↑ Ketone bodies reabsorption
 •
Pathophysiology ... of Euglycemic DKA ... in SGLT2 Inhibitors ... #SGLT2i #Inhibitors ... #pathophysiology
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Medications • SGLT2i ... #Medications #pharmacology ... #pathophysiology ... #endocrinology
Pathogenesis of Diabetic Ketoacidosis - Insulin deficiency or severe insulin insensitivity 

#DKA #Pathophysiology #Endocrinology #Diabetes #Ketoacidosis
insensitivity #DKA ... #Pathophysiology ... #Endocrinology
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors ... - Pharmacology ... ketoacidosis (DKA ... #Inhibitors #Pharmacology ... DM2 #diabetes #endocrinology
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Metformin + SGLT2 ... dapagliflozin) Dpp4 + SGLT2 ... Tablets #Oral #DM2 #Pharmacology ... #Pills #Endocrinology
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
Pathogenesis and Pathophysiology ... Ketoacidosis (DKA ... details of the pathophysiology ... #Pathophysiology ... #Diabetes #Endocrinology
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... Ketoacidosis (DKA ... Polydipsia #dka ... #hhs #pathophysiology ... #comparison #endocrinology