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lfts transaminitis algorithm aih autoimmune biliary causes chemistry cholangitis dehydrogenase elevated function gap globulin hematology hepatomegaly interpretation laboratory lactate ldh
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - Differential ... Diagnosis Framework ... • NAFLD • Cirrhosis ... injury) • Ischemic ... #Diagnosis #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Diagnosis Algorithm ... Metastases • Lymphoma ... Non-Malignant • Fatty Liver ... Primary Biliary Cirrhosis ... #Causes #Hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... CMV), Alcoholic cirrhosis ... #Injury #hepatology ... transaminitis #differential ... #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... cell lung CA, lymphoma ... : < 1 • Cirrhosis ... #injury #hepatitis ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
PBC Signs and Symptoms ... bile ducts Differential ... Viral hepatitis, ... Endocrinopathy, Lymphoma ... #workup #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... : < 1 • Cirrhosis ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
disease to acute liver ... - Symptoms of ... injury, though ... Anti-LKM & Anti-ALC ... #Management #Hepatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... RBCs, muscle, liver ... Malignancy: • Lymphomas ... associated with any symptoms
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Amyloidosis • Lymphoma ... Sarcoidosis) • Liver ... disease: Cirrhosis ... Gap #ProteinGap #differential ... #diagnosis #hematology
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