18 results
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... and clinical associations ... trigger - Direct skin ... - Ice cube test ... Urticaria #diagnosis #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Systemic and Primary Causes ... Liver Function Tests ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #causes
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... Nail Fold Abnormality ... • Nephrotic syndrome ... #Diagnosis #Algorithm ... #causes
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Clinical ... Diagnosis: • + Clinical ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
AIHA Primary Secondary ... Syndrome (CAS): ... Viral Infection Clinical ... • Diagnostic Test ... #anemia #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... matter, spinal cord ... (Clinical Dx). ... (this is a skin ... signs #symptoms #rheumatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
algorithm. ... urgent referral to secondary ... presence of metabolic syndrome ... or referral to secondary ... #Hepatology #Liver
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Liver Function Tests ... Myelodisplastic syndrome ... #Pruritus #secondary ... #causes
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Differential Diagnosis Algorithm ... • Loose anagen syndrome ... decalvans - Secondary ... to Skin Disease ... #causes
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... : • Clinical triad ... • Autoimmune diseases ... Type III Often Secondary ... diagnosis #types #classification