23 results
Janeway Lesions in Endocarditis seen on Physical Exam 

Dr Supradip Ghosh
@dr_supradip

36 year old male with history
Blood cultures growing ... sister shared these photos ... Infective Endocarditis ... #PhysicalExam #clinical ... #photo #dermatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Internal (RBC) - Infections ... - Peripheral Blood ... Smear ↑ abnormal ... #Diagnosis #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
: < 1% Clinically ... of peripheral blood ... ) Differential ... cultures, including blood ... neutrophil #WBC #CBC #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... deficiency - Abnormal ... : • Complete blood ... • Fecal occult blood ... Algorithm #Causes #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... reticularis Differential ... cell arteritis Infections ... vasculitis (inflamed blood ... Polyangiitis #GPA #dermatology
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
Vulnificus skin infection ... vulnificus part of normal ... rash #cellulitis #dermatology ... #legs #clinical ... #photo
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
e.g., HIV), EBV infection ... Autoimmune diseases • Clinical ... Etiology: - Infections ... also arise in normal ... #hematology
Ulcerative Blastomycosis Skin Lesion
57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
heaped up borders); differential ... Indiana University Infectious ... Blastomycosis #SkinRash #dermatology ... #clinical #photo
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... disease • Infectious ... Chest CT: • Ground-glass ... levels are within normal ... hypogammaglobulinemia #immunology #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Clinical Presentation ... Immunoglobulin M (IgM) • Blood ... younger pts) Differential ... sensitize red blood ... hemolytic #anemia #hematology