32 results
Disseminated Cutaneous Blastomycosis- A fungal culture of skin tissue was negative; however, a skin biopsy showed
fungal culture of skin ... staining confirmed a diagnosis ... pyogranulomatous fungal infection ... #clinical #photo ... #derm #NEJM #cutaneous
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
Sporotrichiosis Infection ... wax and wane; diagnosis ... trauma leads to skin ... systemic signs, labs normal ... #clinical #photo
Janeway Lesions in Endocarditis seen on Physical Exam 

Dr Supradip Ghosh
@dr_supradip

36 year old male with history
Blood cultures growing ... Infective Endocarditis ... could have been diagnosed ... #photo #dermatology ... #soles #skin
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... • Major blood ... has five major clinical ... • Cutaneous infection ... have positive blood
Cutaneous larva migrans skin Rash
25 F recent Caribbean vacation, walked barefoot on sand and now with
with creepy rash. diagnosis ... self-limited Diagnosis ... is clinical & labs ... #dermatology #clinical ... #photo
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
: < 1% Clinically ... of peripheral blood ... cultures, including blood ... likelihood of negative clinical ... neutrophil #WBC #CBC #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Clinical Presentation ... presentation) • Cutaneous ... Immunoglobulin M (IgM) • Blood ... sensitize red blood ... hemolytic #anemia #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Arthralgia/arthritis, Skin ... Differential Diaqnoses ... : • Infectious ... management #treatment #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
cooled from the normal ... which can plug blood ... Cryofibrinogenemia Clinical ... : • + Clinical ... #rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... Syndrome: • Clinical ... Labs/Diagnosis: ... Henoch-Schönlein purpura) • Cutaneous ... classification #rheumatology