13 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... 500 mg QD until normal ... #diagnosis #management ... #hematology #oncology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management ... JAK2 mutation OR Abnormally ... transformation into AML ... #Management #Summary ... #treatment #hematology
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
from antibodies formed ... Antiphospholipid antibodies (aPL ... Anticardiolipin antibodies (aCL ... to be present Treatment ... #management #anticoagulation
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
that are poorly formed ... Pinpoint-sized red spots ... transformation to AML ... progression to AML ... Myelodysplastic #Syndromes #diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
crusade against “Ab”Normal ... Normal saline has ... #foamed #criticalcare ... #management #diagnosis ... #treatment #pharmacology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
complete paralysis of all ... • Weakness: Starts ... Guillain-Barre Diagnosis ... CSF PROTEIN - NORMAL ... #management #treatment
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
carry treatment ... breakdown of glycogen stores ... #diagnosis #differential ... #algorithm #management ... #foamed
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... Histoplasmosis Diagnosis ... Inhalation of spores ... level • A low or normal ... #Management #Infections
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Splenomegaly Diagnosis ... are usually near-normal ... transformation into MDS or AML ... #diagnosis #management ... #hematology