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diagnosis differential algorithm anemia causes hemolytic lymphadenopathy allergy cold disease extravascular focal hemolysis intravascular localized mds myelodysplasia myelodysplastic syndromes testing
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... Metastatic) #Diffuse ... Lymphadenopathy #LAD ... #Causes #Hematology ... #Oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... hemolysis • C3 ... malignancies - B-cell ... hemolytic #anemia #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Differential Diagnosis Algorithm ... Lymphadenopathy #LAD ... #Causes #Hematology ... #Oncology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... Consider sickle cell ... Agglutination - Cold agglutinins ... Consider RBC membrane disorder ... #workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... . primary cold agglutin ... lymphoproliferative disorders ... Extravascular #Causes ... differential #diagnosis #hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
Approach to Elevated ... • CKD/ESRD & CAD ... Eosinophilic GI Disorders ... : • Mast cell ... Differential #Diagnosis #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... caused by blood ... Neutropenia • Platelet Disorders ... Syndromes #diagnosis #hematology ... #oncology
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