9 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Risk factor for Late ... mutations - Down syndrome ... incontinence, apraxia ... AlzheimersDisease #Dementia ... #pathophysiology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Disorder (HAND) ... impairment • HIV dementia ... Pathophysiology ... The clinical syndrome ... #AIDS #Neurology
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
- Ocular syphilis ... nephrotic syndrome ... have positive serology ... dementia. ... roots, causing a syndrome
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Summary Acute AIDP ... Guillain-Barre Pathophysiology ... GQ1b IgG Antibody associated ... management #treatment #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... fluctuations PRES-Associated ... Etiology: • Pathophysiology ... Seizures: Treat with AEDs ... diagnosis #management #neurology
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
Unresponsive wakefulness syndrome ... • Locked-in syndrome ... • Mutism Pathophysiology ... • Vestibulo-ocular ... #PhysicalExam #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... treatment of HIV/AIDS ... be present: • AIDS ... skin lesions, ocular ... Other Pathogens Associated
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
organizing pneumonia, ARDS ... respiratory distress syndrome ... is rare but is associated ... accumulation of lipid-laden ... • Reticular + Nodular
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Itraconazole is the agent ... by culture or serology ... yeast • At risk: AIDS ... Aspergillosis Pathophysiology ... osteoarticular, pulmonary, ocular