8 results
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
functions - Aphaso-apraxo-agnosia ... syndrome - Hippocampal ... atrophy Lewy body dementia ... Frontotemporal dementia ... Workup #Diagnosis #Geriatrics
LOW MOLECULAR WEIGHT HEPARIN (LMWH) DOSING RECOMMENDATIONS (Enoxaparin and Dalteparin):
 - VTE PROPHYLAXIS
 - VTE TREATMENT
ACUTE CORONARY SYNDROME ... #LMWH #Dosing #Anticoagulation ... #Prophylaxis #Pharmacology ... #Management
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... incontinence, apraxia ... AlzheimersDisease #Dementia ... pathophysiology #geriatrics
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... refractory lesions Ocular ... immunosuppressive meds • +/- Anticoagulation ... #Treatment #management ... #pharmacology #
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... present Treatment (EULAR ... Antiphospholipid #Syndrome ... APS #diagnosis #management ... #anticoagulation
Low-dose aspirin and low-molecular-weight heparin in lupus and Antiphospholipid Syndrome (APS) pregnancy

• No previous history of
Antiphospholipid Syndrome ... obstetric APS: EULAR ... Antiphospholipid #Syndrome ... pregnancy #Obstetrics #Anticoagulation ... #LWMH #Dosing #Pharmacology
Evans Syndrome Pharmacology Management 
Corticosteroids
IVIg
Rituximab
Splenectomy
Azathioprine
Cyclophosphamide
Cyclosporin
Mycophenolate
Vinka-alkaloid
Plasma exchange
Transfusion
Anticoagulation
Bone marrow stimulating agents

doi:10.3390/jcm9123851

#Evans #Syndrome #Pharmacology #Management #Medications #comparison #table
Evans Syndrome Pharmacology ... Management Corticosteroids ... exchange Transfusion Anticoagulation ... #Pharmacology # ... Management #Medications
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... SLE • Mikulicz syndrome ... gland) biopsy • Ocular ... lubricants • Pharmacologic ... Rheumatology #Diagnosis #Management