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diagnosis hematology management rheumatology blood photo product reactions skin activation algorithm atlas canimorsus capnocytophaga causes cellulitis erythematosus extravascular hemolysis infection
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... intravascular coagulation (DIC ... microangiopathy: Thrombotic thrombocytopenic ... Extravascular #Causes #differential ... #anemia
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
spherocytosis, Hemolytic ... Thrombotic idiopathic thrombocytopenia ... coagulopathy (DIC ... key #diagnosis #differential ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Schistocytes, thrombocytopenia ... - DIC, TTP, HELLP ... #Anemia #Differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... inflammation • Thrombocytopenia ... /TTP/HUS - Hemolytic ... anemia - Splenomegaly ... #nonpalpable #dermatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Photosensitivity, Butterfly rash ... Joints (90%): Aseptic ... ) Blood (75%): Anemia ... Leucopenia/lymphopenia, Thrombocytopenia
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Canimorsus Skin Rash ... Bandemia, AKI. ... inflammation persist → DIC ... possible Patient's clinical ... #dermatology #clinical
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
vulnificus 🦪 🦀 sepsis ... hemochromatosis, hemolytic ... anemia, CKD, hiv ... #cellulitis #dermatology ... #legs #clinical
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine, DIC ... maculopapular rash ... purpura & severe thrombocytopenia ... Can lead to sepsis ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
pain, dark urine, DIC ... maculopapular rash ... purpura & severe thrombocytopenia ... Can lead to sepsis ... diagnosis #management #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
fever syndromes Clinical ... Fever is the main clinical ... Petechial or purpuric rash ... with leukopenia, anemia ... , and thrombocytopenia
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