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diagnosis hematology causes coagulation prolonged pt acronym aflp bleeding bruising comparison disease disseminated hellp hemostasis hepatitis icp intravascular management mnemonic
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
history of trauma, sepsis ... • Severe Liver ... 100mg/dL) - Heparin ... INR < 2.3 - APTT ... treatment #management #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... intravascularcoagulation (DIC ... amyloidosis #Abnormal ... #hematology #coagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... intravascular coagulation (DIC ... Causes #diagnosis #differential
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
imaging: Normal ... • Histology: Normal-mild ... DIC • Aminotransferases ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... Acquired: • Heparin ... PT/NORMAL PTT: ... ABNORMAL PTT: Prolongation
PLATELETS Mnemonic for Causes of Thrombocytopenia P - Platelet Disorders (DIC, ITP, TTP) L - Leukemia, Lymphoma A -
Platelet Disorders (DIC ... Enlarged Spleen L - Liver ... Toxin (Drug or Heparin-induced ... ) S - Sepsis ... Thrombocytopenia #Differential
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