4 results
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... Causes #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... thrombin inhibitors, heparin ... • Reduced liver ... amyloidosis #Abnormal ... #hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
history of trauma, sepsis ... Thrombocytopenia • Prolonged ... DIC • Severe Liver ... 100mg/dL) - Heparin ... treatment #management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... Acquired: • Heparin ... the PT remains prolonged ... Bruising #Hemostasis #Differential ... #Diagnosis #Hematology