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diagnosis algorithm blood hematology product reactions abnormal causes dili drug elevated gastroenterology idiosyncratic induced liver liverenzymes liverfunctiontests transaminitis transfusion transfusions
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... #Diagnosis #Management ... gastroenterology #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... Drugs • TPN • Sepsis ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Differential #
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... ALT or AST): • US ... Drugs, Infection, Sepsis ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Related Acute Lung Injury ... Occurs between 0-6 hrs ... Can lead to sepsis ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Related Acute Lung Injury ... Occurs between 0-6 hrs ... Can lead to sepsis ... Transfusions #diagnosis #management ... #hematology #reactions
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