15 results
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) (e.g. lupus, CLL ... Extravascular #Causes ... #differential # ... diagnosis #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Antibody Autoimmune Hemolytic ... • Blood smear: Differential ... 2) LOOK FOR a cause ... Anemia #diagnosis #management ... #treatment #rheumatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
decrease in most cases ... WBC count and differential ... hematuria (without casts ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Intraoperative Sepsis - Guidelines for Crises in Anaesthesia

Severe sepsis (hypotension persisting after initial fluid challenge of
likely underlying cause ... Discuss ongoing management ... #Anesthesiology ... Checklist #Diagnosis #Management ... #Workup
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
anaesthesia • Sepsis ... #Hyperthermia #Differential ... #Causes #Anesthesiology ... Checklist #Diagnosis #Management ... #Workup
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
toxicity → 3-10 o Sepsis ... #Hypotension #Differential ... #Anesthesiology ... Checklist #Diagnosis #Management ... #Workup
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... Can lead to sepsis ... Transfusion #diagnosis #management ... #hematology #reactions
Increased Airway Pressure - Guidelines for Crises in Anaesthesia

Using these steps from start to end should
POTENTIAL CAUSES ... Airway #Pressure #Differential ... #Anesthesiology ... Checklist #Diagnosis #Management ... #Workup
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Causes purpura & ... TRALI): Leading cause ... Can lead to sepsis ... Transfusions #diagnosis #management ... #hematology #reactions