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diagnosis causes lfts abnormal acute bilirubin dili drug elevated hyperbilirubinemia idiosyncratic induced inherited liverenzymes liverfunctiontests management transaminitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Injury (DILI) ... #differential # ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... • Infectious: Sepsis ... #Injury #Differential ... Causes #Acute #algorithm ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... Cirrhosis (any) • Congenital ... Others #LFTs #Hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... Infiltrative, Congenital ... #diagnosis #hepatology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
of hemolysis or liver ... injury ... as jaundice on clinical ... #bilirubin #hepatology ... #diagnosis #gastroenterology
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