9 results
Causes of Depressed / Lethargic Newborn - Differential Diagnosis Algorithm
Maternal Related:
 • Drugs (Ex. SSRI)
 •
Congenital: • Birth Injury ... Respiratory Distress Syndrome ... Aspiration • Sepsis ... Other: • Anemia ... #Causes #Peds #Pediatrics
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... change disease • Hematologic ... Treatment Related • Sepsis ... #AKI #Cancer #Oncology ... #Differential #
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Marrow (Toxic injury ... Constitutional Syndromes ... Clinical Presentation ... propylthiouracil) - β-lactam ... #oncology #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... liver or renal injury ... - Compartment syndrome ... 30mmHg) - Severe anemia ... gluconeogenesis Liver Injury
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... with leukopenia, anemia ... Triglycerides • ↑ Lactate ... Diagnosis #Management #Hematology
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... microvascular injury ... possible Patient's clinical ... initially with a beta-lactam-beta-lactamase ... #clinical #photo
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... Hyperbilirubinemia • Elevated lactate ... younger pts) Differential ... #hematology #diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... to local skin injury ... brainstem lesions, aseptic ... (Clinical Dx). ... Behcet disease) Differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Clinical Features ... , APLA, PAC • Aseptic ... lymphopenia, low PLT • Anemia