6 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Wilsons, Pregnancy - AFLP ... Drugs, Infection, Sepsis ... LFTs #Elevated #Abnormal
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... • Pregnancy - AFLP ... disease US — Normal ... Drugs • TPN • Sepsis ... Others #LFTs #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... iMedEducation #AFLP ... Liver #Pregnancy #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
of Pregnancy (AFLP ... Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... #differential # ... diagnosis #icp #HELLP #AFLP
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... ALP, alkaline phosphatase ... mellitus; USS, ultrasound ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
initiation • Differential ... Diagnosis: Infection (sepsis ... 500 mg QD until normal ... APML #diagnosis #management ... #hematology #oncology