14 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... and Type of Liver ... Injury #Medications ... #Differential # ... #LiverInjury #Hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Injury (DILI) ... dose dependent injury ... or symptoms of liver ... #differential # ... gastroenterology #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - Differential ... (>1000): • DILI ... injury) • Ischemic ... #Tests #LFTs #Differential ... #Diagnosis #hepatology
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
GTT, indirect bili ... biopsy Meds: ... - Outpatient meds ... hypotension, shock, sepsis ... Calling #Referral #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... • Iatrogenic: DILI ... #differential # ... diagnosis #algorithm #hepatology
Causes of Depressed / Lethargic Newborn - Differential Diagnosis Algorithm
Maternal Related:
 • Drugs (Ex. SSRI)
 •
Lethargic Newborn - Differential ... Congenital: • Birth Injury ... Aspiration • Sepsis ... Algorithm #Causes #Peds ... #Pediatrics
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute Liver ... Injury - Differential ... • Infectious: Sepsis ... #Injury #Differential ... Acute #algorithm #hepatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
Non-accidental Injury ... cell disease Rheumatology ... involvement Sepsis ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
injury < 26 weeks ... Unconjugated Bili ... > 90% of Total Bili ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Causes of Sudden Unexpected Death in Infancy (SUDI) - Differential Diagnosis Algorithm
Congenital Anomaly / Disorder:
 •
Infancy (SUDI) - Differential ... Pneumonia • Sepsis ... Gastrointestinal infection Injury ... Algorithm #Causes #Peds ... #Pediatrics