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diagnosis neurology apml barre causes differentiation encephalopathy erythematosus gravis guillain guillainbarre hematology hemoptysis inflammatory iris lupus myasthenia myelitis oncology posterior
Hemoptysis - Differential Diagnosis Framework Airways: • Bronchitis • Bronchiectasis • Malignancy: Primary bronchogenic CA, Endobronchial
Hemoptysis - Differential ... Parenchyma: • Infection ... westermani, PNA, Lung abscess ... Aspergillosis • Rheumatic/lmmune ... Cardiac/Vascular: • AVMs
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Pathophysiology: • Immune ... response preceding infection ... Can begin in arms ... Absent Reflexes: Arms ... #diagnosis #management
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
proximal weakness, arms ... life-threatening Differential ... precipitated by: Drugs, infection ... immunosuppressants - Meds ... Gravis #diagnosis #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
activation of an immune ... mediated disease • Immune ... extensors of the arms ... Myelitis #diagnosis #management ... #neurology #differential
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
/Sepsis/Shock, Autoimmune ... edema visualized as ... Reversible course Differential ... Diagnosis: • Infection ... #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... osteomyelitis, cutaneous abscesses ... symptoms such as ... #Differential # ... Diagnosis #Management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... initiation • Differential ... Diagnosis: Infection ... (sepsis), PE, DAH ... APML #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... fibromyalgia) • Infections ... context of primary immune ... , APLA, PAC • Aseptic ... C4 accompanies flares
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