17 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
I see all of these ... promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
#neutrophils #AML ... #Clinical #Hematology ... #Pathology #Smear
Salicylate Toxicity - Diagnosis and Management

Clinical Findings
Pathophysiology
Workup
Treatment

By Stacy Marshall, MD

#Salicylate #Toxicity #Diagnosis #Management #Toxicology #Aspirin #Treatment
Salicylate Toxicity ... Diagnosis and Management ... Clinical Findings ... Marshall, MD #Salicylate ... #Toxicology #Aspirin
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... transformation into AML ... • Aspirin should ... PV #Diagnosis #Management ... Summary #treatment #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
complex → plt activation ... Diagnosis: • Clinical ... D/c all heparin ... non-heparin A/C if clinical ... #Treatment #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... IFN-y) → Excessive activation ... accumulation of clinical ... Assessment • Clinical ... Lymphohistiocytosis #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... fever syndromes Clinical ... Fever is the main clinical ... 5000 to 10,000 ng/mL ... Syndrome #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... excessive macrophage activation ... Ferritin >500 ng/mL ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Lutzomyia verrucarum Clinical ... jaundice ​• Neuro: AMS ... coinfection, toxo reactivation ... Clinical Presentation ... Fever #diagnosis #management
Management of Jehovah's Witness patient in ICU 

Clarify which products may be used 
 - Discuss
Management of Jehovah's ... admission - All ... limit to mission-critical ... as a (including aspirin ... #CriticalCare #Management