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oncology syndrome differentiation hemophilia leukemia lysis tls treatment tumor
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... priapism • Lab values ... sudden death • Lab values ... Syndrome #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... organ dysfuxtion, ICU ... Differentiation #Syndrome #APML ... #diagnosis #management ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... activity • ↓ LAP Score ... ↑ Can develop leukostasis ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
and Management ... severity Treatment - Acute ... Avoid meds that ... though safety assessment ... #hematology
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