7 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
blood collection ... with EDTA Pathophysiology ... ) - Waddling gait ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... = nonspecific (nausea ... Liver #Pregnancy #hepatology ... #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... protein C and S Pathophysiology ... thrombopoietin deficiency ... #treatment #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Phagocytosis of blood ... Cellular immune deficiency ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... , CTLA4 deficiency ... result from low blood ... Anemia #oncology #hematology ... #diagnosis #management
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
recipients w/ IgA deficiency ... Causes purpura & ... TRALI): Leading cause ... Transfusions #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
recipients w/ IgA deficiency ... Causes purpura & ... TRALI): Leading cause ... Transfusion #diagnosis #management ... #hematology #reactions