12 results
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency 
Clinical Diagnosis - Caine Criteria (2 out of 4):
Acute Thiamine (B1 ... ) Deficiency Clinical ... dysfunction and gait ... ataxia is only ... Encephalopathy #Thiamine #B1
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Encephalopathy - Acute B1 ... dysfunction (e.g. gait ... ataxia - usually ... syndrome (chronic B1 ... Encephalopathy #B1
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
thiamine (vitamin B1 ... ) deficiency, commonly ... of confusion, ataxia ... (broad-based gait ... #vitaminB1 #B1 #
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... Haemolytic anaemia, ataxia ... • Thiamine B1 ... #Vitamins #Deficiency
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Pathogenesis and clinical ... share the same pathophysiology ... tolerance • Weight gain ... signs #symptoms #endocrinology ... #pathophysiology
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
hypothyroidism Pathophysiology ... : • T4 deficiency ... fibers Spectrum of Clinical ... Hypothyroid #Myopathy #pathophysiology ... signs #symptoms #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
21-Hydroxylase Deficiency ... Pathogenesis and Clinical ... amount of enzyme deficiency ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency ... Framework and Clinical ... Causes of Thiamine Deficiency ... Ophthalmoplegia - Ataxia ... beriberi #nutrition #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... • Vitamin C deficiency ... Pernicious anemia/B12 deficiency ... collection with EDTA Pathophysiology ... ) - Waddling gait
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
effects including ataxia ... with vitamin B12 deficiency ... The classic clinical ... #Pathophysiology