15 results
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency 
Clinical Diagnosis - Caine Criteria (2 out of 4):
Encephalopathy - Acute Thiamine ... (B1) Deficiency ... dysfunction and gait ... ataxia is only ... Encephalopathy #Thiamine
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Encephalopathy - Acute B1 (Thiamine ... dysfunction (e.g. gait ... ataxia - usually ... - Intravenous thiamine ... glucose without thiamine
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
Korsakoff Syndrome - Thiamine ... Deficiency Wernicke's ... to longstanding thiamine ... of confusion, ataxia ... (broad-based gait
Wernicke Encephalopathy - Triad

Encephalopathy 
 • Disorientation 
 • Indifference 
 • Inattentiveness 
Ocular motor dysfunction
gaze palsies Ataxia ... • Gait • ... Diagnosis #Neurology #Thiamine ... #Deficiency
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency ... Deficiency: • ... production • Deficiency ... Ophthalmoplegia - Ataxia ... beriberi #nutrition #pathophysiology
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Vitamins and Vitamin Deficiency ... Haemolytic anaemia, ataxia ... Vitamins: • Thiamine ... #Vitamins #Deficiency
Micronutrient Deficiencies After Gastric Bypass
Fat-Soluble Vitamins:
 • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
Water-Soluble Vitamins: • Thiamine ... oculomotor dysfunction, gait ... ataxia), Korsakoff ... sensory neuropathy, ataxia
Causes of Gait Disturbance - Differential Diagnosis Algorithm
Sporadic
 • Vascular
 • Infection
 • Toxic
 • Nutrition
Causes of Gait Disturbance ... • Friedrich's Ataxia ... Childhood Catalytic Deficiency ... Childhood Catalytic Deficiency ... Niemann-Pick Disease #Gait
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Dose-dependent tremor, ataxia ... dizziness, diplopia, ataxia ... pruritus, weight gain ... #SideEffects #Pathophysiology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Hypo-Mg2+ • Vitamin deficiency ... (thiamine) Late ... • Vitamin D deficiency ... arrhythmias • Thiamine ... Differential #Diagnosis #Pathophysiology