9 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... incontinence, apraxia ... AlzheimersDisease #Dementia ... #pathophysiology
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
– symptoms and signs ... , Deafness Signs ... slowness, Psychosis/dementia ... , Ataxia, Poverty ... Carpal timel syndrome
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... Risk of Refeeding Syndrome ... CNS: Tremors, Ataxia ... #diagnosis #pathophysiology ... #symptoms #signs
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... TLS #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Guillain-Barre Pathophysiology ... Miller Fisher Syndrome ... Opthaloplegia • Ataxia ... #diagnosis #management
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
impairment • HIV dementia ... Pathophysiology ... The clinical syndrome ... motor slowing and ataxia ... neurocognitive #disorder #dementia
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... • Lhermitte’s sign ... Cramping, Weakness, Ataxia ... Signs and symptoms ... sclerosis #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... • Heerfordt syndrome ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Compartment Syndrome Pearls
A vicious cycle of increased pressure within a facial compartment leading to compression of
Compartment Syndrome ... Pathophysiology: ... rest are late signs ... #diagnosis #management ... #pathophysiology