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diagnosis adrenal insufficiency differential signs symptoms acth addisons breast cosyntropin cushings discharge disease evaluation hypercortisolism hyperthyroidism laboratory stimtest syndrome testing
Adrenal Insufficiency Diagnosis Algorithm Clinical features: - Weight loss, anorexia, Weakness, fatigue, GI distress - Hypotension,
Insufficiency Diagnosis Algorithm ... , only seen in PRIMARY ... test: Steroids ... interact with stim test ... #StimTest #Endocrinology
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH Early am cortisol < 3
Insufficiency Diagnosis Algorithm ... unclear (often the case ... Standard Stim test ... #ACTH #Stimulation ... #Test #Endocrinology
Adrenal Insufficiency Differential Diagnosis Algorithm Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Weakness, fatigue, nausea ... hormone (ACTH) stimulation ... test AND • Baseline ... baseline ACTH - Primary ... #endocrinology
Breast Discharge - Differential Diagnosis Algorithm High Prolactin + Normal TSH • Microprolactinoma • Steroid Hormone Intake
Differential Diagnosis Algorithm ... Pregnancy, Breast Stimulation ... + High TSH • Primary ... #Endocrinology ... #Causes
Diagnosis Adrenal Insufficiency - Algorithm Step 1) Screening Test: 6-8AM Cortisol Level - Early morning cortisol levels
Insufficiency - Algorithm ... : Cosyntropin Stimulation ... Differentiate primary ... consistent with primary ... #Endocrinology
Primary Adrenal Insufficiency: • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
Primary Adrenal ... Insufficiency: • ACTH stimulation ... aldosterone - Low in cases ... autoimmune-mediated primary ... diagnosis #testing #endocrinology
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
aldosterone Causes ... : Most Common Causes ... Tuberculosis: can cause ... present - ACTH stimulation ... addisons #disease #endocrinology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
, oral cavity) Caused ... not a feature of primary ... dexamethasone suppression test ... Imaging: 1) Primary ... signs #symptoms #endocrinology
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
• Insomnia Primary ... T4 • Thyroid stimulating ... Atrial fibrillation/flutter ... hyperthyroidism #causes ... #differential #endocrinology
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