476 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... typically a drug) -> Macrophage ... Cells activate macrophages
Trichomonas on Urine Microscopy
Trichomonas organism adjacent to WBC’s and a macrophage - brightfield with SM stain
to WBC’s and a macrophage ... trichomoniasis #clinical
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... fever syndromes Clinical ... Fever is the main clinical ... : Evidence of macrophage ... Syndrome #Diagnosis #Management
Pathology - Hepatocyte Pigments

Lipofuschin (H&E) 

Alpha-I-antitrypsin globules (PAS-D) 

Mallory's hyaline / Mallory Denk Bodies 

Giant Mitochondria
/ ceroid-laden macrophage ... Pathology #Hepatology #Clinical
Cutis Verticis Gyrata: Idiopathic development of excess folds and furrows within the skin of the head.
Associated
Cutis Verticis Gyrata ... UCSD Catalog of Clinical ... Images #Clinical ... Dermatology #SkinRash #Cutis
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
glucosylceramide in macrophages ... in GBA1 gene Clinical
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Pathogenesis and Clinical ... neutrophils and macrophages
Rare Invasive Yeasts - Species and Antifungal Therapy

Cryptococcus, 
Geotrichum, 
Kodamaea, 
(Pichia)ohmeri, 
Malassezia, 
Pseudozyma, 
Rhodotorula, 
Saccharomyces, 
Saprochaete
Trichosporon, Candida auris ... Antifungal #Therapy #Management
Whipple Disease (Tropheryma whipplei) - Diagnosis and Management 

Caused by: Tropheryma whipplei

Symptoms and Signs:
1. Migratory poly/oligoarthralgia
Diagnosis and Management ... • PAS-positive macrophages ... diagnosis #algorithm #management
Allergic Rhinitis: Pathogenesis and clinical findings

1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Pathogenesis and clinical ... Exposure -> APC (macrophages ... , eosinophils, macrophages