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diagnosis management differential algorithm treatment clinical cardiology pharmacology causes hematology neurology pediatrics peds deficiency nephrology pulmonary workup anemia rheumatology disease
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency • B12 Deficiency: MMA elevated,
Levels in Vitamin B12 ... Deficiency • B12 ... #Homocysteine #B12
Causes of Vitamin B12 Deficiency - Cobalamin Decreased Intake Pancreas: Insufficiency Intestine: SIBO, Celiac disease, IBD, Lymphoma, Amyloidosis, Resection,
Causes of Vitamin B12 ... pylori infection, B12 ... BrighamChiefs #Vitamin #B12
Cobalamin (vitamin B12) In the diet: 5-15 pg/day (min. 1-5) B12 Protein HC pH t B12 Duodenum Stomach 1 B12 R-protein Protein From saliva R-protein Intrinsic factor Pancreas B12 R-Protein Trypsin B12 Terminal ileum B12 IF 2 Specific binding to receptors of
Cobalamin (vitamin B12 ... day (min. 1-5) B12 ... Protein HC pH t B12 ... Terminal ileum B12 ... IF B12 pH >
Autoimmune Gastritis - Pathophysiology Anti-ParietaI Cell, CD4+ T Cells, Autoantibodies -> x Parietal Cells, x HCL, x
Pathophysiology #b12
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... Etiology: • Vit B12 ... who don't take B12 ... - Low Vit B12 ... taleanski #Vitamin #B12
Etiologies of Vitamin B12 Deficiency • Inadequate intake - Rare but seen in very strict vegans
Etiologies of Vitamin B12 ... dissociated vitamin B12 ... develop vitamin B12 ... absorbing vitamin B12 ... with decreased B12
Diagnosing Vitamin B12 and/or Folate Deficiency It turns out that simply measuring serum levels of B12 or
Diagnosing Vitamin B12 ... serum levels of B12 ... with low normal B12 ... people with low B12 ... accumulate in B12
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
form of Vitamin B12 ... inhibition of vitamin B12 ... - Vitamin B12 ... converts vitamin B12 ... patients with vitamin B12
Workup for Vitamin B12 and Folate Deficiency #Workup #VitaminB12 #Folate #Deficiency #FolicAcid #Diagnosis #Macrocytosis #MacrocyticAnemia #Algorithm
Workup for Vitamin B12
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
and a vitamin B12 ... Measures of vitamin B12 ... because if vitamin B12 ... that occur with B12
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