ARMYMED @ARMYMED · 2 years ago
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Cobalamin (vitamin B12) In the diet: 5-15 pg/day (min. 1-5) B12 Protein HC pH t B12 Duodenum Stomach 1 B12 R-protein Protein From saliva R-protein Intrinsic factor Pancreas B12 R-Protein Trypsin B12 Terminal ileum B12 IF 2 Specific binding to receptors of 
Cobalamin (vitamin B12)
In the diet:
5-15 pg/day (min. 1-5)
B12
Protein
HC
pH t
B12
Duodenum
Stomach
1
B12
R-protein
Protein
From saliva
R-protein
Intrinsic factor
Pancreas
B12
R-Protein
Trypsin
B12
Terminal ileum
B12
IF
2
Specific binding to receptors of ileal mucosa
B12
IF
B12
pH > 5.6
Transcellular
#B12 transport (~1-2 ug/day)
TC III
3
Plasma
Liver
Storage
TC II
TCI
Plasma-
"reserve"
Cell metabolism
Excretion
ARMYMED @ARMYMED · 2 years ago
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