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Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Megaloblastic Anemia ... Autoimmune hemolytic anemia ... , Thalassemia Basophilic ... interpretation #clinical ... #anemia
Comparison of basophils and mast cells (in bone marrow). #Basophils #MastCells #Pathology #Marrow #Smear #Microscopy #Comparison #Table
Comparison of basophils ... #Basophils #MastCells ... Comparison #Table #Clinical
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Severe hemolytic anemia ... Sideroblastic anemia ... , Hemolytic anemia ... Hemoglobin H disease • Basophilic
Dacrocytes (tear drop cells) Other poikilocytes resemble a pear or teardrop. The narrow, tapered end may be
may be long or short ... metaplasia, pernicious anemia ... some hemolytic anemias ... #Clinical #Path
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
hepatomegaly • Labs: anemia ... after initial Rx), basophilia
Cotton Wool Spots Caused by microinfarcts. Exploded ganglion cell axons extrude their axoplasm into retina. Long DDx:
Cotton Wool Spots ... diabetes, HIV, severe anemia ... #CottonWool #Spots ... ophthalmology #Clinical
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... TlBC > 18% • Anemia ... MCV/RBC<13, +/- basophilic ... #Microcytic #Anemia
Allergic Rhinitis: Pathogenesis and clinical findings 1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Pathogenesis and clinical ... nasal mucosa and basophils ... mast cells and basophils ... > Mast cells & basophils
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... thalassemia, S Lepore • Basophilic ... ARUPLabs #Hemolytic #Anemia
Elliptocyte - Note the shape of these appropriately named erythrocytes. In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... sideroblastic anemia ... iron deficiency anemia ... #Clinical #Path
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