41 results
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing ... in Hemolytic Anemia ... Extravascular Hemolysis ... #Anemia #Laboratory ... #Testing #workup
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Microangiopathic hemolytic ... anemia (e.g. ... Microspherocytes: Autoimmune hemolytic ... anemia Sickled ... , Thalassemia Basophilic
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... thalassemia, S Lepore • Basophilic ... ARUPConsult @ARUPLabs #Hemolytic ... #Anemia #Differential ... workup #hematology #testing
Common RBC Inclusions and Associations
 • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia
 • Heinz
Asplenism, Severe hemolytic ... anemia • Heinz ... Sideroblastic anemia ... , Hemolytic anemia ... Hemoglobin H disease • Basophilic
Coombs Test - Direct vs Indirect

#Diagnosis #Testing #Coombs #Direct #Indirect #Hemolytic #Anemia
#Diagnosis #Testing ... Direct #Indirect #Hemolytic ... #Anemia
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic ... anemia. ... Microangiopathic hemolytic ... anemia is characterized ... coagulation and other testing
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
• Symptoms of anemia ... anemia • Cold ... Positive Coombs testing ... post infectious setting ... #anemia #hematology
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
from shearing, tearing ... to be seen in hemolytic ... anemias, especially ... microangiopathic hemolytic ... anemia in which
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
Iron Deficiency Anemia ... patients with anemia ... biopsy only if serology ... Non-invasive testing ... Iron #Deficiency #Anemia
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SEROSITIS - RENAL - NEUROLOGIC ... - HEMOLYTIC ANEMIA ... the absence of hemolytic ... anemia #Diagnosis