11 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... underlying liver disease ... Coagulation Failure Infections ... Drug-Induced Liver Injury
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Parenchyma • Infectious ... , TPN • Infectious ... Sophia_Hayes_MD #Liver #Injury ... #algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... • Infectious: HAV ... : < 1 • Cirrhosis ... #diagnosis #algorithm
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... • HIV/HCV co-infection ... HBV infection with ... severe liver injury ... > 3 mg/dL) or acute
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... Hepatocellular: Viral infections ... Alcohol-related liver disease ... dechallenge • Acute
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
concentrations in: RBCs ... : • Early acute ... hepatitisAcute ... Hepatocellular Injury ... • Toxins • Infection
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
presents with acute ... to 12 weeks for acute ... extrapulmonary disease ... or meningitic disease ... , neutropenia, cirrhosis
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... - Screen for infection ... injury with serum ... - Concomitant diseases
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Without treatment ... manifestations including acute ... hepatitis and nephrotic ... to asymptomatic infection ... Diseases - https
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
worsening of that disease ... pericarditis, peritoneal disease ... ocular lesions: keratitis ... progression of cirrhosis ... Calmette-Guérin (BCG