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diagnosis differential management infectiousdiseases cardiology infections lactate renal acidosis causes classification dehydrogenase diuresis diuretics elevated elevation excretion fungal fusarium laboratory
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Microbiology: Blood ... Culture (+): Acute ... Cerebral > Splenic, pulmonary ... Septic Emboli Cause Injury ... • Blood cultures
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
concentrations in: RBCs ... deficiency of red blood ... • Pulmonary infarction ... : • Early acute ... hepatitis • Acute
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... Inflammatory eye disease ... quantify renal injury ... reveals increasing blood ... diagnosis #management #treatment
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Microbiology: Blood ... Culture Positive: • Acute ... Cerebral > Splenic, Pulmonary ... Septic emboli cause injury ... hematuria, + RF Treatment
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Torsemide) • Acute ... pulmonary edema ... hyperaldosteronism • Acute ... Prevention of blood ... Tolvaptan) • Treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
removal from the blood ... presentations and disease ... liver or renal injury ... pulmonary edema ... peritonitis - Acute
Fusarium Infections Acquired through: 1. Inhalation of airborne conidia > germinates > blood > disseminated 2. Trauma (implantation with
> germinates > blood ... BCx+ in -40% of ... Refractory FUO, Sino-pulmonary ... : • Optimal treatment ... on the type of injury
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
presents with acute ... to 12 weeks for acute ... • Major blood ... arthritis, and endocarditis ... have positive blood
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