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management differential disease erythematosus lupus systemic algorithm behcet calcium cerebritis cppd deposition fungal hematology hiv infections infectiousdiseases leukemia mnemonic mycoses
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... , Headache, Movement ... Meningitis, Myelopathy, Encephalopathy ... #CNS #neurology ... #rheumatology #
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
papilledema • Horner syndrome ... • Hypertensive encephalopathy ... brain lesion • CNS ... arteritis • Acute ... #Algorithm #neurology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... symptoms (headache ... Oral aphthae : SLE ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Posterior Reversible Encephalopathy ... characterized by: • Headache ... mental status • Headache ... , ADEM, Acute toxic ... #Syndrome #diagnosis
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Syndrome Acute ... Symptoms: • Headache ... Fever (75%) • Encephalopathy ... • New onset SLE ... antibody test) Treatment
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... Blast Phase: • Headaches ... : CNS manifestations ... • Tumor lysis syndrome ... #Oncology #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Differential Diagnosis ... Pleural effusions • Acute ... and CNS • Headache ... #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... 50 years • New headache ... affects the skin, neurologic ... chorioretinitis, CNS ... #Rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
culture used to diagnose ... Pseudogout: Treatment ... Crowned Dens Syndrome ... pain, fever, and headache ... Deposition #Disease #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
presents with acute ... cough, chills, headache ... pulmonary symptoms • Rheumatologic ... especially the CNS ... MC: CNS CSF: •
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