11 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome, Headache ... Meningitis, Myelopathy, Encephalopathy ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Posterior Reversible Encephalopathy ... characterized by: • Headache ... mental status • Headache ... may precede the neurologic ... syndrome, ADEM, Acute
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
with response to treatment ... hypergammaglobulinemia, ↑ acute ... IgG4+ cells" Treatment ... maintenance with GCs ... #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
have fever - ACS ... , AKI, acute limb ... organ damage • Treatment ... Syndrome #TLS #diagnosis ... #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... Philadelphia - BCR-ABL ... Blast Phase: • Headaches ... #Leukemia #Hematology ... #Oncology #Diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... CNS symptoms (headache ... ) Differential Diagnosis ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Vasomotor" symptoms — Headache ... Splenomegaly Diagnosis ... A conclusive diagnosis ... Thrombocythemia #ET #hematology ... #hematology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... claudication, headaches ... of the steroid treatment ... Treatment of GCA ... them, but urgent rheumatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Gout - Diagnosis ... Fluid Testing: • WBCs ... gout treatment; ... #management #treatment ... #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
culture used to diagnose ... Pseudogout: Treatment ... pain, fever, and headache ... Deposition #Disease #Rheumatology ... #diagnosis #management