17 results
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
of lgE Abs that bind ... reactionType ... reactionType ... reactionType ... #Types #Classification
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... Antibodies that bind ... reaction. ... complexes bind ... histamine) into the blood
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
lgE antibodies bind ... - Red blood cell ... with mismatched blood ... #Classification ... #Diagnosis #Reactions
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... and Treatment Types ... drug reaction - ... #Types #Diagnosis ... #Treatment #management
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... lgM antibodies bind ... #types #allergy ... #table #classification
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... released during an allergic ... reaction or asthma ... Or Inflammatory Reactions ... #hematology #basophils
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... for secondary causes ... eosinophilia (common causes ... are asthma, allergy ... , drug reaction,
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Pager Summary Type ... type and detects ... - Allergic ... Transfusions #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Allergic reaction ... Causes purpura & ... TRALI): Leading cause ... Transfusion #diagnosis #management ... #hematology #reactions
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
maintained fever CAUSES ... transfusion • Allergic ... reaction / anaphylaxis ... • Intracranial blood ... Checklist #Diagnosis #Management