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Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
Antibodies that bind ... leading to an allergic ... reaction. ... complexes bind ... #Immunology #pathophysiology
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Penicillin-induced drug reaction ... Dermatitis (ie. reaction ... #Allergic #Reactions ... Classification #Diagnosis
Allergic Reaction Classification Type 1 reaction: Acute anaphylactic reaction Type 2 reaction: Cytotoxic reaction Type 3 reaction: Immune complex Type
Allergic Reaction ... Type 2 reaction ... #Allergic #Reaction ... Classification #Types #allergy ... #diagnosis
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
of lgE Abs that bind ... reaction • Type ... An allergic reaction ... #Allergic #Reactions ... Classification #Diagnosis
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Allergic reaction ... Initial exposure to allergen ... #Immunology #pathophysiology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... syndrome, POEMS • Reaction ... post-splenectomy, Exercise, Allergic ... reactions Matthew ... #Differential #Diagnosis
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
lgE antibodies bind ... When the specific allergen ... Classification #Pathophysiology ... #Allergy #Diagnosis ... #Reactions #Table
Angioedema - Classification Diagnosis and Treatment Types of Angioedema: • Acute allergic angioedema - Usually occurs with
Classification Diagnosis ... Angioedema: • Acute allergic ... exposure • Non-allergic ... drug reaction - ... Classification #Types #Diagnosis
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
hypersensitivity reactions ... Mechanism of Action: Allergen-specific ... lgM antibodies bind ... Acute transfusion reaction ... #types #allergy
Algorithm for the Evaluation and Management of Transfusion Reactions This algorithm was developed by Dr. Eric Madden,
of Transfusion Reactions ... #Transfusion #Reactions ... #Algorithm #Diagnosis ... #Management #Hematology
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