44 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... causes are asthma, allergy ... , drug reaction, ... Differential #diagnosis #hematology ... #eosinophilia
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Antibodies that bind ... leading to an allergic ... reaction. ... complexes bind ... #Immunology #pathophysiology
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Drug Reaction with ... Eosinophilia and ... associated with allergic ... Images #Clinical #Dermatology ... #DrugReaction #Eosinophilia
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Drug Reaction with ... Eosinophilia and ... associated with allergic ... Images #Clinical #Dermatology ... #DrugReaction #Eosinophilia
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... DRESS - AIN - Eosinophilic ... Allergies): - Allergic ... Rhinitis - Allergic ... Diagnosis #Causes #hematology
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
of lgE Abs that bind ... reaction • Type ... reaction • Type ... An allergic reaction ... #Allergic #Reactions
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Allergic reaction ... Initial exposure to allergen ... #Immunology #pathophysiology
Allergic Rhinitis: Pathogenesis and clinical findings

1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Allergic Rhinitis ... Allergy Sensitization ... (neutrophils, eosinophils ... proliferation of eosinophils ... Rhinitis #Rhinorrhea #pathophysiology
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
Eosinophils (Eos ... causes: - Drug reaction ... infection - Allergic ... reaction - Atopic ... + T cells) - Allergic
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... syndrome, POEMS • Reaction ... post-splenectomy, Exercise, Allergic ... reactions Matthew