34 results
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Antibodies that bind ... leading to an allergic ... reaction. ... complexes bind ... #Immunology #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Allergic reaction ... Initial exposure to allergen ... #Immunology #pathophysiology
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
of lgE Abs that bind ... reaction • Type ... reaction • Type ... An allergic reaction ... #Allergic #Reactions
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
When antigens bind ... antibody-mediated immune reaction ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... syndrome, POEMS • Reaction ... post-splenectomy, Exercise, Allergic ... reactions Matthew
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Immune Reactions ... #Pharmacology #Pathophysiology ... #immunology
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... Mechanism of Action: Allergen-specific ... lgM antibodies bind ... Acute transfusion reaction ... #types #allergy
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
lgE antibodies bind ... When the specific allergen ... Classification #Pathophysiology ... #Allergy #Diagnosis ... #Reactions #Table
Anaphylaxis: Treatments (Acute)
Additional Info:
 • IV steroids may be considered for prevention of late phase reactions.
of late phase reactions ... provided, as well as allergy ... Treatments #Management #pathophysiology ... #immunology