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diagnosis dermatology differential algorithm clinical photo skinrash management skin syndrome classification ucsdh causes ddxof dress drugreaction eosinophilia hypersensitivity immunology maculopapular
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
Antibodies that bind ... leading to an allergic ... reaction. ... complexes bind ... #Immunology #pathophysiology
Allergic Contact Dermatitis - Erythematous, indurated, scaly plaques - T-cell mediated, delayed-type hypersensitivity response to exogenous
Allergic Contact ... Contact #Dermatitis #Allergic ... #Allergy #Dermatology ... #Rash #Skin
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
of lgE Abs that bind ... reaction • Type ... reaction • Type ... An allergic reaction ... #Allergic #Reactions
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Allergic reaction ... Initial exposure to allergen ... #Immunology #pathophysiology
Types of hypersensitivity reactions Type I - lgE-Mediated, Within I Hour (Anaphylaxis) Type II - IgG or IgM
hypersensitivity reactions ... Days to Weeks (Rash ... hypersensitivity #reactions ... Classification #Allergy
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
constipation • Allergic ... reaction -> Benign ... Rash • T-cell ... hyponatremia, rash ... #SideEffects #Pathophysiology
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy Mild Reaction - Itching, Minor rash
Mild Reaction ... Itching, Minor rash ... Maculopapular rash ... urticaria OR Unknown reaction ... nephritis, Drug rash
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... syndrome, POEMS • Reaction ... post-splenectomy, Exercise, Allergic ... reactions Matthew
Baclofen Skin Rash When a nursing home patient re-presents to the Emergency Department, go through their medication
Baclofen Skin Rash ... Baclofen #Skin #Rash ... #Dermatology #DrugReaction ... #Allergy #Clinical
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
hypersensitivity reactions ... Mechanism of Action: Allergen-specific ... lgM antibodies bind ... Acute transfusion reaction ... #types #allergy
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