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Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
lgE antibodies bind ... systemic lupus erythematosus ... #Classification ... Pathophysiology #Allergy #Diagnosis ... #Reactions #Table
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Systemic #Lupus #Erythematosus ... #Diagnosis #autoantibodies ... #signs #symptoms ... #differential #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activity that bind ... Labs/Diagnosis: ... systemic lupus erythematosus ... #types #classification ... #rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... • Anti-Ro/SSA autoantibodies ... Kikuchi disease • Type-I ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
systemic lupus erythematosus ... #Pericarditis #Symptoms ... #Signs #Presentation ... #comparison #Table ... #Diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
months) and of autoantibodies ... Systemic Lupus Erythematosus ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
systemic lupus erythematosus ... Presentation - Systemic Symptoms ... purpura: strong sign ... #rheumatology # ... classification