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differential management pancytopenia rheumatology arthritis cbc common cvid disease gap globulin hypogammaglobulinemia immunodeficiency immunology laboratory neutrophil pathophysiology pmr polymyalgia proteingap
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... and Differential Diagnosis ... Algorithm Consumption ... Acquired Aplastic Anemia ... #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... and Differential Diagnosis ... Algorithm Consumption ... Acquired Aplastic Anemia ... #Algorithm #Hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... Normal: < 1% ... Degree of bandemia ... count on initial evaluation ... neutrophil #WBC #CBC #hematology
General Approach to Anemia - Differential Diagnosis Framework 1) Check reticulocyte count to determine if hypo/hyper-proliferative 2) Exclude
General Approach to Anemia ... Framework 1) Check ... guide further evaluation ... uw_IMresidency #anemia ... #hematology #algorithm
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Affects 1:25,000 ... • Infectious diarrhea ... autoimmune hemolytic anemia ... syndrome • Burns • Protein-losing ... hypogammaglobulinemia #immunology #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... CRP level: (1) ... the presence of anemia ... as opposed to 1 ... #diagnosis #testing
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
• An evaluation ... Also consider an evaluation ... and C-reactive protein ... • Normocytic anemia ... #Management #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... Thalassemia, Sickle cell anemia ... #differential #diagnosis ... #hematology
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