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rheumatology erythematosus sle systemic vasculitis activation criteria cryoglobulinemia cryoglobulins differential disease eularacr laboratory macrophage management mas rheumatic rheumatoid syndrome testing
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... • Arthritis domain ... pericarditis • Hematologic ... #EULARACR #Classification ... Erythematosus #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... juvenile idiopathic arthritis ... disease • Systemic lupus ... SJIA], systemic lupus ... Activation #Syndrome #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... Skin Disease Classification ... Differential Diagnosis ... , lymphopenia, low ... Erythematosus #Diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Labs/Diagnosis: ... factor level • Low ... (e.g. systemic lupus ... #types #classification ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... • Complement (Low ... #rheumatology # ... classification
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... chest wall, and low ... back pain) • HLA-B27 ... (to support a diagnosis ... laboratory #workup #diagnosis
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