6 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... Diagnosis via genetic ... Splenomegaly • Low ... #management #treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... , Elevated Cr, Low ... #TLS #diagnosis ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... syndrome, a search ... Presentation • Common Signs ... Pathophysiology ... Low/absent NK-cell
Compartment Syndrome Pearls
A vicious cycle of increased pressure within a facial compartment leading to compression of
Compartment Syndrome ... Pathophysiology: ... pressure → Blood flow ... #diagnosis #management ... #pathophysiology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... alkalosis • Normal or low ... Congenital chloride diarrhea ... #diagnosis #nephrology ... #management #pathophysiology
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
• Boerhaave syndrome ... hormonal imbalances (low ... loss of HCO3- in diarrhea ... Complications #pathophysiology ... #diagnosis #signs