14 results
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
rheumatic fever ... • Chronic - Think ... hepatitis, herpes • Chronic ... = RA, SLE, psoriatic ... #rheumatology #
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Malar rash • SLE ... Dermatomyositis Erythema chronicum ... • Rheumatic fever ... #joint #pain #skin
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
• Rheumatic fever ... streptococci (rheumatic fever ... • SLE • Psoriatic ... Symmetrical: • RA • SLE ... Diagnosis #MSK #rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Fever/Chills/Joint ... - SLE - Behcet ... Reactive Syndrome - Acute ... rheumatic fever ... Effusions: - Hematologic
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Constitutional domain: Fever ... cutaneous lupus • Arthritis ... in at least 2 joints ... pericarditis • Hematologic ... Classification #Criteria #SLE
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Classification: • Acute ... : • Joint pain ... , Fever, Serositis ... with Lupus: • Chronic
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
swelling in weird joints ... arthritic flare ... Chronic CPP Crystal ... 12-24 Hours • Fever ... Gout #Comparison #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... Screening Tests for Acute ... Screening Tests for Chronic ... • Sacroiliac joint
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... Headaches, bone pain, fever ... , joint pain, bleeding ... Lymphadenopathy • HSM • Fevers ... #Leukemia #Hematology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
swelling in weird joints ... Chronic CPP Crystal ... Resembles RA • Chronic ... neck pain, fever ... Deposition #Disease #Rheumatology