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diagnosis differential blood product transfusion algorithm antimda5 antimda5dm antinxp2 antinxp2dm autoimmune complications cutaneous disorders eosinophil eosinophilia findings gout hemeonc hemophagocytic
Cutaneous and Systemic Findings in Dermatomyositis Cutaneous Findings: - Heliotrope sign and edema - Nail-fold changes -
- Heliotrope sign ... or shawl sign ... - Gottron's sign ... - Interstitial lung ... #Diagnosis #Rheumatology
Transfusion Reactions - Summary Cheatsheet • Hemolytic Reaction • Febrile Reactions • Transfusion Related Acute Lung
Transfusion Reactions ... • Febrile Reactions ... Related Acute Lung ... #diagnosis #management ... #hematology #complications
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... #rheumatology # ... dermatology #diagnosis
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... allergy, drug reaction ... organ-specific signs ... Differential #diagnosis #hematology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... shoulders (in a shawl sign ... #diagnosis #management ... #rheumatology # ... dermatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion Reactions ... Related Acute Lung ... potassium from lysed cells ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
common immune reaction ... Related Acute Lung ... potassium from lysed cells ... Transfusions #diagnosis #management ... #hematology #reactions
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
WBC >100k, + lab signs ... Lysis of tumor cells ... TLS #diagnosis #management ... #hematology
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
Diagnosis and Management ... A reaction to phagocytosed ... double contour sign ... +Radiographic signs ... #treatment #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... • Interstitial lung ... Myositis #Myopathy #rheumatology
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